Negative health impacts associated with CBD products have also been reported. After testing, the products were found to be tainted with a synthetic cannabinoid. Synthetic cannabinoids were also associated with 153 illnesses and four deaths in Illinois in 2018. Information based on proven scientific evidence about products made from cannabis is limited.
General clinical recommendations of reducing substrate doses, monitoring for ADEs, and finding alternative therapy should be considered, especially in medically complex patients. CBD is implicated as both a victim and perpetrator of DDIs and has its own ADE profile.
Further research is required to determine whether this could lower Plavix’s effectiveness in preventing heart attacks. Patients taking Eliquis should speak to their doctor before using CBD products.
‘If you have a health condition, or are taking any prescribed or over-the-counter medicines, always check with your doctor or a pharmacist for possible drug supplement interactions before taking CBD,’ says Dr Brewer. ‘This is because CBD interacts with enzymes involved in metabolising some medicines and may result in increased drug levels that could cause side effects. Unlike the most well-known cannabinoid, tetrahydrocannabidiol (THC), CBD is not psychoactive, meaning that it won’t make you ‘high’ – the sensation most commonly associated with cannabis.
Across the Atlantic, Geoffrey Guy, the founder of a company called GW Pharmaceuticals, had successfully brought one cannabis-derived medicine, called Sativex, to market in Britain and other European countries. The first such medication permitted by a government, it was approved to treat the symptoms of spasticity (as well as pain) caused by multiple sclerosis, a progressive autoimmune disease of the central nervous system. Guy was intrigued when, through a mutual acquaintance, a California family seeking CBD to treat epilepsy reached out to him — Evelyn Nussenbaum and her son Sam. Modern scholars hemp oil for pain argue that his demonizing cannabis both justified his position and provided a way for him to gain legal leverage over peoples he despised. The high cost paid by people of color, once he had begun what we now call “the war on drugs,” may not have been an incidental byproduct of his efforts but an unstated goal from the start.